Sugar acids and derivatives
Medchemexpress LLC PROTAC BET Degrader-10 | 1957234-97-7 | 99.4% | 783.29 | 1 ML
PROTAC BET Degrader-10 (dBET37) is a potent BET protein BRD4 degrader, connected by ligands for Cereblon and BRD4, with a DC50 of 49 nM. This compound utilizes PROTAC technology, containing two different ligands connected by a linker; one for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Potent BET protein BRD4 degrader
- Connected by ligands for Cereblon and BRD4
- DC50 of 49 nM
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
- For research use only
- Components include a BRD4(BD1BD2) ligand, a Cereblon ligand, and a linker
- Appearance is a solid
- Color is off-white to light yellow
Medchemexpress LLC Semaglutide-FITC (semaglutide-Lys(FITC)) | 4502.96 | 25 MG
Semaglutide-FITC is a FITC-labeled semaglutide, a GLP-1R agonist. It is used to directly track the distribution, cellular uptake, and transmembrane transport processes of vesicles. It can also be employed to study the movement and penetration ability of mixed vesicles in porcine intestinal mucus in vitro.
- FITC-labeled semaglutide (a GLP-1R agonist).
- Directly track the distribution, cellular uptake, and transmembrane transport process of vesicles via fluorescence imaging and flow cytometry.
- Study movement and penetration ability of mixed vesicles in porcine intestinal mucus in vitro.
Medchemexpress LLC 4-methylumbelliferyl α-D-galactopyranoside | 38597-12-5 | M65400 | 99.8% | 338.31 g/mol | C16H18O8 | 25 MG
4-Methylumbelliferyl-α-D-galactopyranoside is a pro-fluorogenic substrate for α-galactosidase that releases fluorescent 4-methylumbelliferone (4-MU) upon enzymatic cleavage, enabling sensitive fluorometric detection in biochemical and enzymatic assays. Supplied as a powder with documented solubility in DMSO and defined storage conditions for stability.
- Fluorogenic substrate for α-galactosidase assays.
- Generates fluorescent 4-methylumbelliferone on enzymatic cleavage.
- High purity (99.8%) suitable for biochemical assays.
- Soluble in DMSO (≈33.3 mg/mL) for preparation of stock solutions.
- Stable when stored as powder at -20°C for long-term storage.
Medchemexpress LLC [D-Trp34]-Neuropeptide Y | 153549-84-9 | 99.7% | 4311.72 | 10 MG
[D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. It is significantly less potent at the NPY Y1, Y2, Y4, and y6 receptors. This product markedly increases food intake in rats.
- Potent and selective neuropeptide Y (NPY) Y5 receptor agonist.
- Markedly increases food intake in rats.
Medchemexpress LLC Interferon alpha/beta receptor 1 Antibody (YA3833) | Predicted band size: 64 kDa; Observed band size: 110-130 kDa | 50 UL
The Interferon alpha/beta receptor 1 Antibody (YA3833) is a mouse-derived, non-conjugated IgG1 monoclonal antibody that targets Interferon alpha/beta receptor 1. This antibody is intended for research use only. Interferon alpha/beta receptor 1 (IFNAR1), in conjunction with IFNAR2, forms the heterodimeric receptor crucial for type I interferon signaling. Binding of type I interferons initiates the JAK-STAT signaling cascade, which leads to the transcriptional regulation of interferon-regulated genes that mediate the interferon response.
- Host: Mouse
- Clonality: Monoclonal antibody
- Species reactivity: Human, mouse
- Conjugation: Non-conjugated
- Isotype: IgG1
- Appearance: Liquid
- Formulation: Supplied in PBS with 0.05% sodium azide
- Purity: Affinity purified
- Storage: Stored at -20°C for 1 year. Avoid repeated freeze/thaw cycles.
- Applications: WB, IHC-P, FC, ELISA
Medchemexpress LLC Heparin sodium salt (MW 15kDa) | 9041-08-1 | 15000 (Average) | 1 G
Heparin sodium salt (MW 15kDa) is a polymer of Heparin with an average molecular weight of 15kDa. It functions as an anticoagulant by reversibly binding to antithrombin III (ATIII), significantly accelerating ATIII's rate of inactivating coagulation enzymes thrombin factor IIa and factor Xa.
- Induces an angiogenic response (increased vascularization) in a late Chorioallantoic Membrane (CAM) assay.
Medchemexpress LLC [Ala11,D-Leu15]-Orexin B(human) | 532932-99-3 | 98.3% | 2857.26 | 10 MG
[Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist, demonstrating a 400-fold selectivity for OX2 (EC50=0.13 nM) over OX1 (52 nM).
- Potent and selective OX2 agonist
Medchemexpress LLC (S)-Ibuprofen acyl-β-D-glucuronide | 98649-76-4 | 98.5% | 382.40 | 1 MG
(S)-Ibuprofen acyl-β-D-glucuronide is a compound used to study the metabolism and pharmacokinetics of S-ibuprofen, which is a non-steroidal anti-inflammatory drug. It is an acylglucuronic acid metabolite produced from S-ibuprofen in the liver. This product is intended for research use only.
- Used for studying metabolism.
- Used for pharmacokinetic research.
- Derived from a common anti-inflammatory drug.
- Metabolite produced in the liver.
Medchemexpress LLC Integrin alpha 6 bet 100ug
Integrin alpha 6 beta 1 Protein Human (HEK293 Flag-His) is the recombinant human-derived Integrin alpha 6 beta 1 protein expressed by HEK293 with C-His C-Flag labeled tag has molecular weight of 110 130 kDa respectively
Medchemexpress LLC Integrin alpha 5 bet 10ug
ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Flag C-10 His labeled tag Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) has molecular weight of 101 35 kDa
Medchemexpress LLC Heparin calcium | 37270-89-6 | MFCD00131296 | ≥98.0% | 3600-5000 | Not specified (heterogeneous polysaccharide; no single chemical formula) | 25 MG
Heparin calcium (MW 3600-5000) is a low-molecular-weight heparin anticoagulant supplied for research use. It binds antithrombin III to inactivate thrombin and other activated clotting factors, preventing fibrin formation. The material is provided as a white to off-white solid with good aqueous solubility and is intended for laboratory assays involving anticoagulation or coagulation pathway studies.
- Intended for research use only.
- Anticoagulant that binds antithrombin III to inhibit coagulation.
- Molecular weight range 3600-5000.
- Supplied as a white to off-white solid.
- Soluble in water (≈200 mg/mL with ultrasonication).
- Store sealed and dry at 4 °C; in solution, store at -20 °C to -80 °C per guidelines.
- Typical purity ≥98% (batch-specific certificate of analysis available).
- Available in small laboratory package sizes (example: 25 mg).